Feline Inflammation (SAA)
Serum amyloid A (SAA) is a major acute-phase protein in cats that rises rapidly during inflammation. Quantitative fSAA measurement supports early detection and monitoring of inflammation, but does not identify its cause. Point-of-care testing can return serial SAA values during treatment monitoring, helping confirm whether therapy is working.
Fact Table
| Species | Feline |
|---|---|
| Biomarkers | Feline Serum Amyloid A (fSAA) |
| Tests |
Clinical Context
Serum amyloid A (SAA) is a major acute-phase protein in cats that rises rapidly during inflammation. Quantitative fSAA measurement supports early detection and monitoring of inflammation, but does not identify its cause. Point-of-care testing can return serial SAA values during treatment monitoring, helping confirm whether therapy is working.
Interpretation should combine the quantitative result with the patient's signalment, history, clinical signs, vaccination or treatment history where relevant, and any other laboratory findings. A single value is rarely diagnostic on its own; serial measurements often provide more useful information.
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2026-09-12
MEDIUM
FAQ
What are CRP and SAA?
C-reactive protein (CRP) and serum amyloid A (SAA) are acute-phase proteins produced rapidly during inflammation. CRP is the primary inflammatory marker in dogs, while SAA is preferred in cats, where it rises faster and returns to baseline sooner after treatment.
Do CRP and SAA identify the cause of inflammation?
No. They are non-specific markers that quantify the amount of inflammation but do not identify its cause. They are most useful for detecting inflammation, tracking response to treatment, and catching complications early — not for pinpointing the underlying disease.
Which is better for monitoring treatment?
For cats, serial SAA is an excellent monitor of treatment response because it falls quickly once therapy is effective — a falling value confirms the treatment is working before the patient looks better.